{"id":229,"date":"2013-12-05T11:42:43","date_gmt":"2013-12-05T00:42:43","guid":{"rendered":"http:\/\/localhost\/rettaustralia\/?page_id=229"},"modified":"2021-04-05T15:39:22","modified_gmt":"2021-04-05T05:39:22","slug":"who-gets-rett-syndrome","status":"publish","type":"page","link":"https:\/\/rettaustralia.org.au\/about-rett-syndrome\/who-gets-rett-syndrome\/","title":{"rendered":"Who gets Rett syndrome?"},"content":{"rendered":"<p>Almost every person diagnosed with Rett syndrome is female.<\/p>\n<p>The <em>MECP2<\/em> gene, mutations of which are the main cause of Rett syndrome, lies within band Xq28 on the X chromosome. A female born with a <em>MECP2<\/em>mutation on her X chromosome has another X chromosome with an apparently normal copy of the <em>MECP2<\/em> gene. On the other hand, a male with a mutated <em>MECP2<\/em> gene on his X chromosome has no other X chromosome, only a Y chromosome, thus he does not have a normal <em>MECP2<\/em> gene to fall back on. Male foetuses with an <em>MECP2<\/em> mutation are believed to die before birth. However, there are a small number of live males with a genetic change in their <em>MECP2<\/em> gene who have developed signs and symptoms like those seen in Rett syndrome, including intellectual disability, seizures, and movement problems, some of whom have been diagnosed with Rett syndrome.<\/p>\n<p>The incidence of Rett syndrome in Australia is 1:9,000 live female births. The disorder is not restricted to any race or ethnic group.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Almost every person diagnosed with Rett syndrome is female. The MECP2 gene, mutations of which are the main cause of Rett syndrome, lies within band Xq28 on the X chromosome. [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":1151,"menu_order":40,"comment_status":"closed","ping_status":"open","template":"","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","ngg_post_thumbnail":0,"footnotes":""},"taxonomy_info":[],"featured_image_src_large":false,"author_info":{"display_name":"Gary Grocott","author_link":"https:\/\/rettaustralia.org.au\/author\/garyg\/"},"comment_info":0,"_links":{"self":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/229"}],"collection":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/comments?post=229"}],"version-history":[{"count":1,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/229\/revisions"}],"predecessor-version":[{"id":5646,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/229\/revisions\/5646"}],"up":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/1151"}],"wp:attachment":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/media?parent=229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}