{"id":225,"date":"2013-12-05T11:41:28","date_gmt":"2013-12-05T00:41:28","guid":{"rendered":"http:\/\/localhost\/rettaustralia\/?page_id=225"},"modified":"2021-09-22T18:49:20","modified_gmt":"2021-09-22T08:49:20","slug":"what-causes-rett-syndrome","status":"publish","type":"page","link":"https:\/\/rettaustralia.org.au\/about-rett-syndrome\/what-causes-rett-syndrome\/","title":{"rendered":"What causes Rett syndrome?"},"content":{"rendered":"<p>Rett syndrome is caused by MECP2 gene mutation at the time of conception.<\/p>\n<p>In October 1999, it was discovered by researchers at the Baylor College of Medicine in Houston that mutation of the&nbsp; <em>MECP2<\/em> gene is the main cause of Rett syndrome. To date, mutation of the MECP2 gene has been found in 95% of individuals who have been diagnosed with the disorder. It is not known why these mutations occur.<\/p>\n<p>The <em>MECP2<\/em> gene contains instructions which enable genes to function properly. If the <em>MECP2<\/em> gene is not functioning properly, it allows genes to turn on or off at inappropriate times, thus disturbing the precisely regulated sequence necessary for proper development of a human&rsquo;s central nervous system.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Rett syndrome is caused by MECP2 gene mutation at the time of conception. In October 1999, it was discovered by researchers at the Baylor College of Medicine in Houston that [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":1151,"menu_order":42,"comment_status":"closed","ping_status":"open","template":"","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","ngg_post_thumbnail":0,"footnotes":""},"taxonomy_info":[],"featured_image_src_large":false,"author_info":{"display_name":"Gary Grocott","author_link":"https:\/\/rettaustralia.org.au\/author\/garyg\/"},"comment_info":0,"_links":{"self":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/225"}],"collection":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/comments?post=225"}],"version-history":[{"count":2,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/225\/revisions"}],"predecessor-version":[{"id":6089,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/225\/revisions\/6089"}],"up":[{"embeddable":true,"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/pages\/1151"}],"wp:attachment":[{"href":"https:\/\/rettaustralia.org.au\/wp-json\/wp\/v2\/media?parent=225"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}